Marfan syndrome (MFS) is a heritable multisystemic disorder with a spectrum of clinical manifestations primarily linked to variants in the Fibrillin-1 ...

Those close to Jonathan Gant say he’s a man with a big heart—and now it needs mending. On Dec. 24, his life changed ...

Talfirastide is under clinical development by Constant Therapeutics and currently in Phase II for Ischemic Stroke.

Examples are some hereditary cerebral amyloid angiopathies, connective tissue diseases (e.g., as Marfan's disease and Ehlers–Danlos disease) and thromboembolic diseases (e.g., homocystinuria or ...

Sean has learning difficulties and lives with Marfan Syndrome – an inherited disorder that can cause, among other things, skeletal, eye and back problems. He moved with his parents and five younger ...

When Geoff Lester suddenly felt dizzy while refereeing a basketball game in Brisbane, the then 24-year-old didn’t make much of it. When the spell hadn’t passed an hour later, a friend insisted he go ...

The 2023 study by Nakamura and colleagues, published in Arteriosclerosis, Thrombosis, and Vascular Biology, represents a significant advancement in our understanding of aortic root aneurysm formation ...

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Fibrillin-1 mutations have also been found in patients who do not fulfil clinical criteria for the diagnosis of Marfan syndrome, but have related disorders of connective tissue, such as isolated ...