The Marfan Foundation and Baylor College of Medicine are conducting the multicenter Aortic Valve Operative Outcomes in Marfan Patients study (AVOMP) to compare the outcomes of aortic valve-sparing ...

The interesting coincidence of the publication of two similar case reports of Marfan's syndrome in this ... and their covert aortic disease was not revealed until they were involved in accidents ...

The standard treatment for the connective tissue disorder Marfan's syndrome (MFS) is β-blockade, aimed at reducing aortic wall stress. Angiotensin II type 1 and 2 receptors (AT 1 and AT 2 ...

Several genetic conditions, such as Marfan syndrome, Loeys-Dietz syndrome, Turner syndrome, and bicuspid aortic valve can also increase risks. Other risk factors can include using illegal ...

If the aneurysm is > 5.0 cm and there is a connective tissue disorder present (Marfan’s syndrome, bicuspid aortic valve etc...), then surgical repair is indicated.

Connective tissue disorders such as Marfan’s syndrome, Turner’s syndrome, Ehlers-Danlos syndrome and bicuspid aortic valve have a significantly increased risk of aortic dissection. The onset ...

Transgenic mouse models of Marfan syndrome exposed a surprising and crucial function of elastic extracellular matrix components in regulating TGFβ signalling. By interacting with unprocessed ...

At this time, recruitment for extended follow-up is complete. Manifestations of the Marfan syndrome appear in many parts of the body, especially in the bones and ligaments (the skeletal system), the ...