The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging ... calcium dynamics and calcium-sensitisation mechanisms, ... Myosin Light Chain ...

The pathophysiology of heart failure is complex, but mitochondrial dysfunction is an emerging therapeutic target to improve cardiac function. In this Consensus Statement, insights into the ...

Many people who have suffered a heart attack subsequently develop life-threatening complications like ventricular fibrillation. Now an international research team from the University of Freiburg's ...

Evidence that many positive inotropic interventions are accompanied by increased potassium efflux from the myocardium, 13 along with earlier observations that high potassium concentrations inhibit the ...

During embryonic development, thousands of cells divide and move collectively, sculpting the main body axes from an initially ...

The experimental image shows two proteins -- myosin (cyan) and actin (red) -- in a chick embryo during gastrulation, highlighting the main body axes and the dominant force-generating regions (cyan).

This article was originally published with the title “ The Mechanism of Muscular Contraction ” in Scientific American Magazine Vol. 213 No. 6 (December 1965), p. 18 doi:10.1038 ...

However, the molecular mechanisms by which Rho family proteins induce reorganization of the actin cytoskeleton are not fully understood. Recently, WASP ( W iskott– A ldrich s yndrome p rotein) family ...

BACKGROUND Atropine, an anticholinergic agent with central and peripheral actions, reduces gastro-oesophageal reflux (GOR) in normal subjects and patients with gastro-oesophageal reflux disease (GORD) ...