Marfan syndrome (MFS) is a heritable multisystemic disorder with a spectrum of clinical manifestations primarily linked to variants in the Fibrillin-1 ...

whereby mutant fibrillin monomers impair the global function of the microfibrils. In this paper we review the molecular physiology and pathophysiology of Marfan syndrome and related ...

Some of the more common musculoskeletal causes of rib cage pain are described ... Risk factors include the condition Marfan's syndrome as well as cardiovascular disease. Sleep apnea may also ...

Pectus excavatum (PECK-tuss ex-kuh-VAW-tum) is a condition that causes a child’s chest to look sunken or ... Rarely, they also have Marfan syndrome. You may see a small dent in your child’s chest when ...

Possible explanations for why your ribs hurt can include injuries, inflammation or infection, and referred pain from other organs that you feel in the rib cage area, like the kidneys. Rib pain is ...

There are many causes of sudden cardiac death ... arrhythmogenic right ventricular cardiomyopathy, and aortic rupture in Marfan syndrome, and will also identify non-familial abnormalities such as ...

Scoliosis causes a sideways curvature of your spine ... Birth defects and other genetic conditions, such as Marfan syndrome and Down syndrome, can also lead to scoliosis. Many people who have ...

Transgenic mouse models of Marfan syndrome exposed a surprising and crucial function of elastic extracellular matrix components in regulating TGFβ signalling. By interacting with unprocessed ...

The White House contradicts a new intelligence assessment on the mysterious ailments that diplomats and spies have reported ...

New intelligence has led two US intelligence agencies to conclude that it’s possible a small number of mysterious health ...

Irritable bowel syndrome (IBS) is a gastrointestinal (GI) disorder that causes symptoms like abdominal pain and bloating, as well as bowel movement changes like diarrhea, constipation, or both.