It's not looking quite as good for the Wall Street open as it did in the early hours. The S&P 500 at one stage had been in line for a 0.5% gain, the Dow Jones Industrial Average was eying a 0.4% ...

Optinose shares took flight in premarket trading Thursday after the pharmaceutical company agreed to be acquired by privately held Paratek Pharmaceuticals in a deal worth up to $330 million.