About TGFBI Corneal Dystrophy. TGFBI corneal dystrophy is a group of genetic eye disorders caused by mutations in the TGFBI gene, resulting in abnormal protein buildup in the stromal layer of cornea.

About TGFBI Corneal Dystrophy. TGFBI corneal dystrophy is a group of genetic eye disorders caused by mutations in the TGFBI gene, resulting in abnormal protein buildup in the stromal layer of cornea.

According to the company, TGFBI corneal dystrophy is a genetic disorder that leads to the accumulation of abnormal proteins in the cornea’s stromal layer, with symptoms being loss of vision ...

Slit lamp examination revealed bilateral corneal stromal edema and corneal guttata consistent with Fuchs' endothelial dystrophy. Six months after the initial diagnosis, the patient underwent ...

CASE REPORT. A 56 year old white female emmetrope (20/20 both eyes) presented with photopsia secondary to posterior vitreous separation. Bilateral, thin (<0.5 mm), grey-white, granular but continuous, ...

GenEditBio Limited has announced the first patient has been dosed in an investigator-initiated trial (IIT) of GEB-101, an in vivo genome editing program for TGFBI corneal dystrophy.. TGFBI corneal ...

This trial marks the world's first clinical study of an in vivo CRISPR-Cas ribonucleoprotein (RNP)-based genome editing investigational therapy for TGFBI corneal dystrophy.