Beta thalassemia intermedia: The affected person has symptoms that fall between the minor and major categories, such as moderate anemia, and may require intermittent red blood cell transfusions.

Beta thalassemia major. This is a more severe form of thalassemia that’s also called Cooley’s anemia. ... With beta thalassemia minor, you may have no symptoms.

Also known as beta thalassemia trait, people with beta thalassemia minor inherit only one HBB gene variant (mutation). Affected people usually do not experience symptoms—and if they do it is ...

There are three main types of the disease: beta thalassemia major, intermedia, and minor. All of them happen because of a mutation (change) of the HBB gene. Transfusion-dependent Beta Thalassemia.

Some people with thalassemia major may need regular blood transfusions. However, the CDC states that those with thalassemia minor do not typically need transfusions because they may not have ...

Beta thalassemia minor: ... Beta thalassemia major: This form causes severe anemia, which can lead to potentially life-threatening complications without treatment.

beta-thalassemia minor: You may have mild anemia and small red blood cells. ... The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: The UCSF registry.

Bank A, Marks PA: Excess alpha chain synthesis relative to beta chain synthesis in thalassemia major and minor. Nature (London) 212:1198–1200, 1966. Crossref. PubMed. Web of Science.

For beta thalassemia minor in particular, iron overload isn’t a problem, but other thalassemias can cause iron overload. So, giving iron can be harmful for some.