The San Francisco 49ers (6-10) are 4.5-point underdogs as they try to break their three-game losing streak in a matchup against the Arizona Cardinals (7-9) on Sunday, January 5, 2025 at State Farm

San Francisco (6-10) rides a three-game losing streak into a matchup with (-) on Sunday, January 5, 2025 at State Farm Stadium. The Cardinals are listed as favorites in this one, with the spread

The San Francisco 49ers (6-10) head to State Farm Stadium to take on the Arizona Cardinals (7-9) to close their 2024 NFL season. The 49ers will look to end the season on an uptick before h