Senate Majority Leader John Thune can afford to lose three Republican senators and still pass the bill, and there are more than that, right now, who have problems with it. Like the House, he will have to balance the concerns from moderate and conservative members of his conference.

The House-passed reconciliation bill containing most of President Donald Trump’s agenda won’t clear the Senate in its current form. CQ Roll Call’s Caitlin Reilly, Peter Cohn and David Lerman outline the changes that could be on the table and the competing demands among Senate Republicans that will make final passage a tough slog.

Speaker Mike Johnson struck a series of delicate deals to get the GOP's “big, beautiful bill” through the House. Now, Senate Republicans are threatening to tear them apart.