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ALS drugs from Denali, Calico come up short, marking setback for Healey trial
Denali’s medicine and a similar one from Calico Life Sciences and AbbVie were not much different than a placebo, bringing the tally of failed drugs in the innovative “Healey platform trial” to seven.
HEALEY ALS Trial Serves Up More Disappointment as Denali, AbbVie/Calico Fail
Misses from amyotrophic lateral sclerosis hopefuls Denali Therapeutics and partners AbbVie and Calico Life Sciences mark the latest setbacks for the controversial platform trial, the results from which have largely mirrored the dismal success rate in the ALS space overall.
Denali Therapeutics' ALS drug fails in mid-to-late stage trial
Denali Therapeutics said on Monday its experimental drug failed to meet the main goal of a mid-to-late stage trial involving patients with amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease.
Denali Therapeutics announces HEALEY ALS trial regimen misses endpoints
Denali Therapeutics (DNLI) announced topline results from an analysis of Regimen G of the Phase 2/3 HEALEY ALS Platform Trial evaluating eIF2B
STAT
18h
Pharma’s big patent cliff, more obesity fundraising, and a failed ALS study
STAT reporters discuss why a looming patent cliff could lead to more pharmaceutical deal-making and a new obesity startup.
The Pharma Letter
1d
Calico next to fail in ALS
Calico Life Sciences, a biotech founded by Alphabet and Arthur Levinson focused on the biology of aging and age-related ...
FierceBiotech
3d
Rival AbbVie and Denali prospects flunk phase 2/3 ALS tests, denting hopes for shared mechanism
AbbVie, Calico and Denali Therapeutics’ hopes of treating amyotrophic lateral sclerosis (ALS) by targeting eIF2B have all ...
STAT
2d
Google’s secretive anti-aging company Calico finally released data. Its drug failed
The company said Monday that fosigotifator failed to outperform placebo in slowing the neurodegenerative disease, but is ...
12h
on MSN
Southern California small businesses offering to help fire victims
Small businesses in Los Angeles and the surrounding counties have offered help to people affected by the fires raging in the ...
4d
Maple Street Biscuit Co. co-founder launching competing brunch taco and coffee concept
Twelve years after launching the successful Maple Street Biscuit Co. chain, co-founder Scott Moore is set to debut a new and ...
DreamTeamsWorld on MSN
14h
Calico Critters Spooky Surprise House #asmr #calicocritters #gifted
Prepare for an epic food journey as I explore Las Vegas's largest buffet: the famous Bacchanal Buffet inside Caesars Palace! Today, I’m diving into their brand-new Crab Brunch, packed with endless ...
Hosted on MSN
2d
Fierce bird attacks calico cat lurking under its tree
A fierce bird attacked a calico cat lurking under its tree territory. Footage shows the oriental magpie robin swooping down ...
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