RB Jordan Mason filled in admirably to start the year, but he was hit with a shoulder injury in Week 6 that he battled until ...

The San Francisco 49ers are going to have a fourth different starting running back this season according to a report from ...

Reporting emerged earlier on Thursday noting that 49ers running back Isaac Guerendo is unlikely to play in Sunday's game ...

Guerendo has rushed for 381 yards and four touchdowns this season. The 49ers are also likely to again be without left tackle ...

San Francisco 49ers running back Isaac Guerendo is unlikely to play in Sunday's game against the host Miami Dolphins, ESPN ...

Coach Kyle Shanahan said Monday that the 49ers expect Guerendo (foot/hamstring) to practice Thursday, Nick Wagoner of ESPN.com reports.

When will Isaac Guerendo return and play? Will Isaac Guerendo be back again this season? Read the latest Isaac Guerendo injury updates and return date for Week 17 (2024).

Guerendo (foot, hamstring) has been ruled out for Sunday's game at Miami, Matt Maiocco of NBC Sports Bay Area reports. Guerendo didn't practice this week and thus appears in danger of missing time ...

San Francisco 49ers running back Isaac Guerendo is "unlikely to play" against the Miami Dolphins, according to ESPN insider ...

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.

Isaac Guerendo faces an uphill climb if he wants to suit up on Sunday vs. the Dolphins after suffering a hamstring injury ...

The rookie running back did not practice last week and has been officially ruled out of Sunday’s clash at Hard Rock stadium ...