The engineered human myocardium exhibits Frank-Starling–type force-length relationships. After 2 weeks of static stress conditioning, the engineered myocardium demonstrated increases in contractility ...

Daniel Aiham Ghazali, Caroline Delaire, Emmanuel Blottiaux, Jean-Yves Lardeur, Daniel Jost, Mathieu Violeau, Cyril Breque, Denis Oriot, Development of a Performance Assessment Scale for Simulated ...

To describe the reporting of cointerventions and to evaluate the factors associated with their reporting, we did a systematic search of all RCT s evaluating pharmacological interventions on ...

Background: Venous thromboembolism (VTE) is a life-threatening vascular event with environmental and genetic determinants. Recent VTE genome-wide association studies (GWAS) meta-analyses involved ...

Visit-to-visit variability (VVV) of blood pressure (BP) is associated with increased risk for stroke, coronary heart disease (CHD), and mortality. 1 – 5 The mechanisms underlying the association ...

To determine the role of endothelium-mediated flow-dependent coronary dilatation in humans, we studied the coronary dilatation exerted by maximal pharmacologic increase of coronary flow in 14 patient ...

Background—Framingham-based and Reynolds Risk scores for cardiovascular disease (CVD) prediction have not been directly compared in an independent validation cohort. Methods and Results—We selected a ...

Measurement of blood pressure (BP) in the upright posture is recommended by all hypertension guidelines to detect orthostatic hypotension especially in elderly patients. 1 However, a number of studies ...

To align with its mission to reduce the global burden of raised blood pressure (BP), the International Society of Hypertension (ISH) has developed worldwide practice guidelines for the management of ...

Background— Apelin is among the most potent stimulators of cardiac contractility known. However, no physiological or pathological role for apelin–angiotensin receptor-like 1 (APJ) signaling has ever ...

Background— Abnormal intercellular communication caused by connexin dysfunction may be involved in atrial fibrillation (AF). The present study assessed the effect of the gap junctional conduction–enh ...

From the Department of Social and Preventive Medicine, State University of New York at Buffalo, Buffalo, NY. Background—This study examined whether a supervised exercise program improved 19-year ...