Background Data regarding long-term recovery from autoimmune encephalitis (AE) remain limited. Methods This retrospective ...

Background Alexander disease is an autosomal dominant leukodystrophy caused by heterozygous pathogenic variants in the glial ...

Despite the learning opportunities afforded by on-call experiences, high associated workloads often contribute to trainee dissatisfaction. High workloads can also result in delayed decision-making, ...

Background Extended interval dosing (EID) of natalizumab is a promising strategy to optimise treatment in multiple sclerosis (MS). Personalised EID by therapeutic drug monitoring can enable further ...

Background Benign multiple sclerosis (MS), characterised by minimal disability despite long disease duration, remains poorly understood in terms of its determinants and prognostic implications. While ...

Objective To examine pre-existing anxiety disorders as a risk factor for increased concussion symptomology and prolonged recovery in children and adolescents. Methods In this retrospective cohort ...

Recent publications showed that circulating neurofilaments (Nfs) may be used as a diagnostic biomarker distinguishing amyotrophic lateral sclerosis (ALS) from ALS mimics with high sensitivity and ...

Gamma frequency stimulation is found to alleviate memory deficits on animal models of Alzheimer’s disease (AD), potentially by activating neuroimmune signalling and removing A-beta plaques in the ...

Background Fatigue is a disabling symptom of multiple sclerosis (MS). The lack of effective therapeutics has promoted the development of cognitive behavioural therapy (CBT)-based fatigue management ...

Background Data on cognition in patients with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are limited to studies with small sample sizes. Therefore, we aimed to analyse the ...

Objective Dysfunction of the blood–nerve barrier (BNB) plays important roles in chronic inflammatory demyelinating polyneuropathy (CIDP) and multifocal motor neuropathy (MMN). The aim of the present ...

Background SARS-CoV-2 mRNA vaccination of healthy individuals is highly immunogenic and protective against severe COVID-19. However, there are limited data on how disease-modifying therapies (DMTs) ...