The EMBO Journal5d
Nuclear PD-L1 triggers tumour-associated inflammation upon DNA damage
PD-L1 not only responds to the cGAS-STING pathway upon DNA damage, but also regulates cGAS-STING to induce inflammation. This ...
The EMBO Journal1d
Schizophrenia-related Xpo7 haploinsufficiency leads to behavioral and nuclear transport pathologies
XPO7 haploinsufficiency increases the risk of schizophrenia. In the mouse nervous system, it disrupts nuclear export or ...
The EMBO Journal5d
Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentation
Hypoxia contributes to cancer resistance to both standard therapies and immunotherapy. This work demonstrates that tumor ...
The EMBO Journal5d
Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...
The EMBO Journal5d
MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mitochondrial carrier homolog 2 (MTCH2) is a ...
The EMBO Journal4d
The proximity-based protein interactome and regulatory logics of the transcription factor p65 NF-κB/RELA
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. TFs are key components of gene regulatory ...
The EMBO Journal3d
Structure of the Nipah virus polymerase complex
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Nipah virus is a highly virulent zoonotic ...
The EMBO Journal5d
A phosphorylation-regulated NPF transporter determines salt tolerance by mediating chloride uptake in soybean plants
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chloride ions are important inducers of salt ...
The EMBO Journal5d
The proximity-based protein interactome and regulatory logics of the transcription factor p65 NF-κB/RELA
This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets by Stacey D. Gilk, Rajendra Angara and Arif Sadi. The ...
The EMBO Journal5d
Partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Biogenesis of membrane-bound organelles ...
The EMBO Journal6d
A therapeutic regimen using neoantigen-specific TCR-T cells for HLA-A*2402-positive solid tumors
This month's cover highlights the article JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia by Karoline Strobl, Maria Sibilia, Thomas Bauer and ...