Synchronization of brain cells underlies the generation of key motor functions including breathing, cardiac activity and locomotion. The circuitry mechanisms underpinning this phase-locked rhythmic ...

Cardiac arrest, a sudden cessation of heart function, demands immediate intervention to prevent death. Survival rates, ...

Sudden muscle contractions called hypnic jerks, experienced by up to 70% of adults, can disrupt sleep. These harmless 'sleep ...

The calmodulin antagonist W7 binds to troponin C in the presence of Ca2+ and inhibits striated muscle contraction. This study integrates multiple data into the structure of the regulatory domain of ...

Cardiologists caution against excessive use of gourmet salts. Himalayan pink salt and sea salt are under scrutiny. These ...

Seismocardiographic (SCG) signals are chest wall vibrations that correlate with cardiac activity and often measured using accelerometers on the chest surface [1]. SCG may be generated by valve ...

In cardiac muscle, the contractions occurring after short pauses are potentiated (20). In several species these PRCs usually become reduced in force as the rest periods increase (32). The rat cardiac ...

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In comparison to 430 genes with H3K9Ac enrichment observed in DMSO-treated cells, which were mainly involved in cardiac muscle contraction (Fig. 7G and H), 2C treatment markedly enhanced the ...

This work was supported by a Grand‐in‐Aid (#15GRNT23070001) from the American Heart Association (AHA), 2 Founders Affiliate Post‐doctoral Fellowships (#15POST22690003 and #12POST9310001) from the AHA, ...

An abundance of evidence points to the sarcomere as a key site for mechanotransduction. The sarcomere is the basic contractile unit of cardiac muscle, and it is made up of a complex assembly of ...

These results suggest that while the modifications in the cRp region have minimal influence, those in the key functional cIp-cSp region have a pronounced effect on the interaction of cTnI and cTnC, ...