Using Cockayne Syndrome (CS) as a model of accelerated aging, we demonstrate that CSB-deficient cells exhibit chromatin decompaction, increased PARylation near transcription start sites, and ...

Several human neurological and neuromuscular diseases are caused by the expansion of repetitive DNA tracts. Understanding the DNA metabolic processes responsible for the expansion (or lengthening ...

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Neuroscience research. Learn how the brain's physical, chemical and electrical structure can affect everything from motivation and sensory perception to disease recovery.