We confirmed an association of anti-dsDNA and anti-SSA/Ro52 antibodies with disease activity in SLE. In MCTD, there was an association of anti-Sm/RNP B and -RNP68 antibodies with pulmonary disorder.

Background The mixed connective tissue disease (MCTD) is an autoimmune systemic disease characterised by clinical manifestations that are included in systemic lupus erythematous (SLE), scleroderma ...

For example, connective tissue disorders (CTDs ... associated autoantibodies were associated with myositis and overlap syndromes as well as systemic lupus erythematosus (SLE) and Sjögren’s Syndrome ...

med.uni-heidelberg.de In the following case series, we present four patients with different connective tissue diseases (CTD ... Two patients with SLE and active glomerulonephritis were treated with ...

But while those functions address the top and bottom of the funnel, the middle of the funnel has been underserved. “The connective tissue in the middle — the consideration element of the funnel — has ...

Body fat, particularly fat under the skin, known as subcutaneous adipose tissue (SAT), plays a crucial ... increasing the risk of diabetes and cardiovascular disease. Through identifying these ...

Connective tissue diseases are a heterogeneous group of autoimmune disorders that affect any of the body's connective tissues. These disorders can be inherited or acquired, and can present with a ...

Kidney cancer-- also called renal cell cancer-- is a disease in which kidney cells become ... A doctor may use a needle biopsy to remove a sample of tissue, which is then examined under a ...

and active SLE disease, according to a study published online Feb. 25 in JAMA Network Open. Yoo Jin Kim, M.D., from Johns Hopkins University in Baltimore, and colleagues examined the frequency of and ...

When her symptoms persisted, the possibility of an underlying connective tissue disorder such as systemic lupus erythematosus (SLE) was explored and confirmed. Despite the initiation of ...

Her Systemic Lupus Erythematosus Disease Activity Index score was 10. Her medical history included 2 years of therapy with methotrexate and cyclosporine, which had been discontinued due to elevated ...