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Telomeropathies: here is a cause of accelerated aging ⏳The ends of chromosomes, called telomeres, shorten with age. They function like a molecular clock for the cell. Premature shortening of these DNA sequences is the cause of genetic diseases ...
Early findings showed EXG-34217 successfully lengthened CD34+ cell telomeres by 1.24-fold ex vivo in a patient with dyskeratosis congenita, a telomere biology disorder that can lead to bone marrow ...
His new study shows that specific defects in RNA translation underlie a progressive disease called dyskeratosis congenita. It involves multiple organ systems and includes premature aging and ...
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