Among members of the Richardson family who carry a mutation in the PSEN1 gene, the average age when symptoms start is 39.

Poor dietary patterns, including high intake of sugary and ultra-processed foods, are linked to increased early-onset colorectal cancer (EOCRC) risk. Sedentary lifestyles and excessive screen time ...

I'm afraid, then, to report that Light No Fire watchers are likely entering the early stages of what I'm calling Silksong Syndrome—the uncontrollable craving that consumed fans of Hollow Knight ...

Among over 263,000 participants, the incidence of CRC was 26.1 per 100,000 person-years for those who participated in early screening (at ages 40 to 49) versus 42.6 per 100,000 person-years for ...

Background In patients presenting with acute cardiac symptoms, abnormal ECG and raised troponin, myocarditis may be suspected after normal angiography. Aims To analyse cardiac magnetic resonance (CMR) ...

Symptoms of Werner syndrome, which causes premature aging, can appear in a person's teens and progress quickly in their 20s and 30s. ... Some early-onset cancers are on the rise.

Objective The incidence of early-onset colorectal cancer (EO-CRC) is steadily increasing. Here, we aimed to characterise the interactions between gut microbiome, metabolites and microbial enzymes in ...

### What you need to know A 32 year old woman presented to her GP with a four week history of a prolapsing anal lump after defecation. She had a normal body mass index and a history of anxiety, ...

A recent study reveals rising early-onset colorectal cancer rates, highlighting disparities and the need for improved ... (20% vs 15%), and of Hispanic/Latino ethnicity (11% vs 8%) compared with those ...

Between 1990 and 2021, the prevalence of early onset CRC increased from 29.65 to 38.86 per 100,000. ... with the most common being Lynch syndrome (for young onset its 10-20%) ...

CRC also exemplifies the challenges of understanding early-onset cancer, as it can be affected by genetic factors, notably Lynch syndrome, as well as lifestyle and changes in the environment.