Patients with ejection fraction <40% were excluded ... placebo on the functional status of elderly patients with diastolic heart failure. [21] This was a smaller study that enrolled 74 patients ...

Chronic heart failure occurs when either the left ... HFpEF connotes diastolic dysfunction despite a normal ejection fraction. Diastolic dysfunction also occurs frequently in patients with HFrEF.

Diastolic heart failure is defined clinically when signs and symptoms of heart failure are present in the presence of preserved left ventricular systolic function (ejection fraction >45%).

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Medically reviewed by Christopher Lee, MD Diastolic dysfunction is a heart condition that happens when there is a “stiffening ...

The Food and Drug Administration (FDA) has accepted for Priority Review the supplemental New Drug Application (sNDA) for finerenone for the treatment of ...

Inter-atrial shunt device therapy has shown mixed results in clinical trials, with clinical 'non-responders' typically showing features of more advanced heart failure. We aimed to analyse the ...

Of note, diastolic heart failure disproportionately affects women, particularly elderly women. ‘These data confirm that heart failure with preserved ejection fraction, also know as diastolic ...

USA: Researchers have found in a recent randomized clinical trial, HuMAIN-HFpEF, that among patients with obesity-related ...

Heart failure with preserved ejection fraction (HFpEF), also called diastolic heart failure, occurs when the heart’s left ...

Chronic heart failure is a syndrome ... including estimation of LV ejection fraction. Diastolic function assessment can help determine the left heart diastolic pressures. The cardiac valves ...