Inter-atrial shunt device therapy has shown mixed results in clinical trials, with clinical 'non-responders' typically showing features of more advanced heart failure. We aimed to analyse the ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Diastolic heart failure is defined clinically when signs and symptoms of heart failure are present in the presence of preserved left ventricular systolic function (ejection fraction >45%).

Background: A metabolic shift from fatty acid (FAO) to glucose oxidation (GO) occurs during cardiac hypertrophy (LVH) and heart failure with reduced ejection fraction (HFrEF), which is mediated by PGC ...

The Graham-Steell murmur remained a universally accepted ... a loud and palpable mitral 1st sound, and an early systolic ejection click at the left sternal border. The pulmonic 2nd sound was ...

People with high blood pressure will have a systolic reading of 130 millimeters of mercury (mm Hg) or above or a diastolic reading of 80 mm Hg or higher. Systolic blood pressure is the pressure ...

In systolic heart failure, this pumping capacity becomes compromised. Medical professionals measure this pumping efficiency through a metric called ejection fraction—the percentage of blood your ...

Coronary heart disease, systolic blood pressure, and C-reactive protein (a measure of inflammation) are predictive of heart failure independent of ejection fraction. Left atrial size, arguably a ...

Assessment of TAPSE (top left panel), S′ (top right panel), and RV‐FAC (low panels) in a sample patient with chronic heart failure and reduced ejection fraction. RV‐FAC indicates right ventricular ...

The birth weight was 1.8 kg. (4 pounds). A systolic murmur was heard at 5 weeks of age. Congestive heart failure was first diagnosed at 8 months of age on the basis of failure to thrive ...

Readings contain two numbers: systolic pressure and diastolic pressure. What Is Blood Pressure? Diastolic Pressure Diastolic pressure is the lower/bottom number in your blood pressure reading. It's ...