Frontiers16d
Advances in the study of nicotinamide adenine dinucleotide phosphate oxidase in myocardial remodeling
Myocardial remodeling is a key pathophysiological basis of heart failure, which seriously threatens human health and causes a severe economic burden worldwide. During chronic stress, the heart ...
eLife16d
Mitochondrial adenine base editing of mouse somatic tissues via adeno-associated viral delivery
The authors have demonstrated the use of adenine base editors delivered via adeno-associated viruses to introduce edits in the mitochondrial genome. The manuscript describes the methodology well, and ...
C&EN1mon
Enzymatic Synthesis of Biflavonoid Glycosides with Enhanced Antitumor Activity Using Glycosyltransferase and Sucrose Synthase
Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, College of Pharmacy, Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan 430061, China Institute for Safflower ...
C&EN1mon
Metal-Assisted Synthesis of Extended Polyaromatic Nitrogen-Rich Ligands for Tunable Sensitization of Eu(III) Complexes
Department of Inorganic and Analytical Chemistry, University of Geneva, 30 quai E. Ansermet, CH-1211 Geneva, Switzerland ...
eLife1mon
MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration
This study by Graca et al. explores ethanol metabolism pathways in mycobacteria. The enzyme, MftG, a flavoprotein dehydrogenase, is shown to act as an electron shuttle between an uncommon redox ...
Frontiers6y
Cancer Stem Cell Metabolism and Potential Therapeutic Targets
for generation of adenosine 5′-triphosphate and nicotinamide adenine dinucleotide. CSCs in tumor under hypoxia: hypoxia-inducible factor-1α (HIF-1α) promotes upregulation and potentiated activity of ...