Recent research shows the bird flu virus may be just a few mutations away from transmitting more readily to humans, which could elevate risk. If you haven’t yet been sick this winter ...

Having two copies of the MTHFR gene mutation may raise your risk for certain health conditions, though more research is needed. You may have the mutation and not find out unless you undergo ...

These findings set the stage for the current studies, which provide the first molecular pictures of KBTBD4 targeting the CoREST complex through interactions induced by both cancer mutations and a ...

As an intrinsic cellular pathway, nonsense-mediated decay (NMD) conceals neoantigens through the destruction of the RNA products from genes harboring truncating mutations. We developed and conducted a ...

Each patient received ≥ one peptide resulting from a frameshift insertion and deletion. Seven patients received a peptide containing a neoantigen derived from a cancer driver mutation ...

The second family identified [NC_000017.11(NM_001042492.2):c.2739_2740del]. According to genotype-phenotype correlation analyses, proband with frameshift mutation tended to have a larger number of ...

Merck & Co.’s Covid-19 pill is giving rise to new mutations of the virus in some patients, according to a study that underscores the risk of trying to intentionally alter the pathogen’s genetic code.

A frameshift variant c.826_827insGGC (p.R275_Q276insR ... We identified 12 reported MFN2 mutations and four novel variants in our cohort. The most frequent variant was c.280C>T (p.Arg94Trp) in exon 4, ...

We find that mutations in almost all cancer driver genes contain remarkably little information on patient prognosis. However, CNAs in these same driver genes harbor significant prognostic power. Focal ...