Scientific organizations recently called for a 10-year ban on human germline editing. But will we ever be ready? And how ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's ...

Those include BRCA1 and BRCA2, which occur in about one of every 500 women and confer an increased risk of breast or ovarian cancer, and rarer mutations in a gene called TP53 that causes a disease ...

Key Takeaways. Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM ...

Unlike so-called somatic gene editing, where one type of cell or tissue (the one where a mutation is wreaking the most havoc and causing disease) is targeted for modification, editing an embryo ...

Intellia plays down concerns about accidental germline transmission ... it was possible to precisely alter the DNA of particular cells within the human body to treat disease with a one-time ...

In December, the FDA approved the first two cell-based gene therapies for treating sickle cell disease: Casgevy and Lyfgenia. And, like any emerging medical technology, the initial use of the ...

CRISPR is a versatile tool for editing genomes and has recently been approved as a gene therapy treatment for certain blood disorders. When you purchase through links on our site, we may earn an ...

Study: Germline-encoded specificities and the predictability of the B cell response.Image Credit: Kateryna Kon/Shutterstock.com Background. Although the evolution of the immunoglobulin genes that ...