Scientific organizations recently called for a 10-year ban on human germline editing. But will we ever be ready? And how ...

Those include BRCA1 and BRCA2, which occur in about one of every 500 women and confer an increased risk of breast or ovarian cancer, and rarer mutations in a gene called TP53 that causes a disease ...

Key Takeaways. Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM ...

Families of those who have sickle cell disease in the Philadelphia area are pushing for more research and a cure.

Pathogenic germline variant discovery in plasma cell disorders: Insights from genetic counseling referrals and testing. Tehilla Brander , Manisha M Balwani , Sundar Jagannath , Samir Parekh , Santiago ...

Unlike so-called somatic gene editing, where one type of cell or tissue (the one where a mutation is wreaking the most havoc and causing disease) is targeted for modification, editing an embryo ...

Study: Germline-encoded specificities and the predictability of the B cell response.Image Credit: Kateryna Kon/Shutterstock.com Background. Although the evolution of the immunoglobulin genes that ...

In December, the FDA approved the first two cell-based gene therapies for treating sickle cell disease: Casgevy and Lyfgenia. And, like any emerging medical technology, the initial use of the ...

CRISPR is a versatile tool for editing genomes and has recently been approved as a gene therapy treatment for certain blood disorders. When you purchase through links on our site, we may earn an ...

CRISPR gene editing means a cure for sickle cell disease is on the horizon. However, the life-changing treatment is likely to remain out of reach for most of those who could benefit.

Intellia plays down concerns about accidental germline transmission ... it was possible to precisely alter the DNA of particular cells within the human body to treat disease with a one-time ...