They’ve discovered a previously unknown organelle – that is, a specialized structure that performs some specific function – inside human cells. The team named it the “hemifusome”, and in a paper ...

Scientific organizations recently called for a 10-year ban on human germline editing. But will we ever be ready? And how ...

Testicular germline tumors affect young male patients. Although they have high survival rates, they also have a higher risk of developing cardiovascular disease (CVD) compared to the general ...

AbstractMotivation:. Tumors of non-small cell lung cancer (NSCLC) patients are heterogeneous entities. Genomic landscapes are influenced by genetic constitution, environmental exposures and the ...

Unlike so-called somatic gene editing, where one type of cell or tissue (the one where a mutation is wreaking the most havoc and causing disease) is targeted for modification, editing an embryo ...

In sickle-cell disease scientists must fix the stem cells that go on to make blood. ... Fetal editing might be able to reach those cells more easily. The lure of germline editing, ...

Key Takeaways. Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM ...

StARD6, which is expressed only in male germ-line cells, thus exhibits biological and biophysical properties that imply a role in steroidogenesis. ... Disorders in the initial steps of steroid hormone ...

The singer Halsey shared a diagnosis of a rare T-cell lymphoproliferative disorder. Learn about what this disorder is, what causes it, and how it's treated.

Those include BRCA1 and BRCA2, which occur in about one of every 500 women and confer an increased risk of breast or ovarian cancer, and rarer mutations in a gene called TP53 that causes a disease ...

Pathogenic germline variant discovery in plasma cell disorders: Insights from genetic counseling referrals and testing. Tehilla Brander , Manisha M Balwani , Sundar Jagannath , Samir Parekh , Santiago ...

Germline cells are responsible for passing genetic information from one generation to the next through the production of eggs and sperm in animals, or pollen and ovules in plants.