are due to its lower affinity for heparin-binding proteins and endothelial cells, shorter fractionated heparin chain (which allows for better bioavailability), and unsaturable renal elimination.

All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

Researchers at the University of Tsukuba have reported on the structure and light energy transfer efficiency of a protein ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to ...

Zoloft (sertraline) has interactions with many types of medications, including other antidepressants, amphetamines, blood ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut ...

A study describes the design of de novo ligand-binding transmembrane proteins, demonstrating their specific binding and activation of fluorogenic ligands. Gasdermin D and gasdermin A3 are pore ...

Identifying and characterizing secreted virulence proteins are fundamental for deciphering ... In this study, Cheng et al., show that heparin sodium modulates Cas12 cleavage activity and apply ...

2 Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy 3 Department of Pharmaceutical Sciences, University of Bologna, Bologna, Italy 4 Department of ...