Background: Unfractionated heparin (UFH) has been used clinically for 5 decades. Despite being a cornerstone of anticoagulation, UFH is limited by its unpredictable pharmacokinetic profile, which ...

A retrospective observational study was conducted among adults hospitalized at Stanford Hospital between February 2009 and August 2009. All samples were simultaneously drawn and aPTT and anti-Xa ...

All the patients had received standard heparin therapy to keep the activated thromboplastin time at 1.5 ... Vienna, Austria) and a fully automated coagulation analyzer (CA 6000, Sysmex, Kobe ...

Heparan sulfate (HS), dermatan sulfate (DS), and heparin are natural glycosaminoglycans (GAG), which are linear polysaccharides, heterogeneous in both sequence and length. 1 GAGs carry out many ...

Despite its limitations for monitoring heparin, aPTT remains the most convenient and most frequently used method for monitoring the anticoagulant response. aPTT should be measured ≈6 hours after the ...

Cohen, E. and Kubinak, N. (2025) A Rare Presentation of Cavernous Sinus Thrombosis in a Young Female. Surgical Science, 16, ...

The heparin effect was more consistently quantified by ROTEM. Background Point of care viscoelastic measures with thromboelastography (TEG; Haemonetics Corporation, Switzerland) and thromboelastometry ...

Leeches might make you squirm, but these small, blood-sucking creatures are making a big comeback in modern medicine. Once a staple of ancient healing methods, leech therapy is now gaining renewed ...

Risk of heparin-induced thrombocytopenia: High: Low: Low: None: Monitoring: Must be monitored with ACT or aPTT; levels correlate with safety and efficacy: Cannot be monitored with ACT/aPTT; may be ...