Several genetic conditions, such as Marfan syndrome, Loeys-Dietz syndrome, Turner syndrome, and bicuspid aortic valve can also increase risks. Other risk factors can include using illegal ...

have a parent, sibling, or child who has a thoracic aortic aneurysm or who has experienced a rupture of an aneurysm or an ...

If the aneurysm is > 5.0 cm and there is a connective tissue disorder present (Marfan’s syndrome, bicuspid aortic valve etc...), then surgical repair is indicated.

Connective tissue disorders such as Marfan’s syndrome, Turner’s syndrome, Ehlers-Danlos syndrome and bicuspid aortic valve have a significantly increased risk of aortic dissection. The onset ...

The standard treatment for the connective tissue disorder Marfan's syndrome (MFS) is β-blockade, aimed at reducing aortic wall stress. Angiotensin II type 1 and 2 receptors (AT 1 and AT 2 ...

Transgenic mouse models of Marfan syndrome exposed a surprising and crucial function of elastic extracellular matrix components in regulating TGFβ signalling. By interacting with unprocessed ...

and postoperative care of patients with aortic aneurysms and dissection, including those resulting from genetic connective tissue disorders, such as Marfan syndrome and Loeys-Dietz syndrome, as well ...