Individuals with inherited connective tissue disorders, such as Marfan syndrome, are particularly at risk, often developing the condition at a young age. This highlights the urgent need for ...

The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which as no cure to date. This ...

Aortic dissection is one of those rare, dangerous conditions that can strike without warning and escalate quickly. It is not something we often hear about, but knowing the signs could save a life.

Marfan Syndrome is a rare genetic condition that affects the body’s connective tissue, the material that supports and holds together skin, bones, blood vessels, and organs. When this tissue is ...

Her dad, Dave Holden, was 60 years old when he passed away in 2022 from an aortic dissection. Known by his family as "Big Dave", he was never diagnosed while alive.

Penny had a large dissection of his aorta that needed to be repaired immediately. By 4 a.m., he was in surgery having a new aortic arch put it and its connection to major blood vessels repaired.

In Marfan's syndrome, connective-tissue alterations promote aortic aneurysm and dissection. Despite advances in understanding the causes, treatments are still based on old protocols. The ...

A mutation in the fibrillin-1 (FBN1) gene causes Marfan syndrome. The FBN1 gene helps provide your connective tissues with strength and flexibility. How Does Marfan Syndrome Affect the Heart & Blood ...

Surgery for Marfan syndrome is aimed at preventing aortic dissection or rupture and treating problems affecting your heart's valves, which control the flow of blood in and out of your heart and ...

Marfan syndrome increases the risk for aortic dissection, where the aorta splits suddenly after becoming enlarged. "It is often lethal, and when the patient survives, urgent surgery is needed ...

Aortic Dissection Symptoms The signs of aortic dissection can be similar to those of other diseases. Or you could feel like you’re having a heart attack. But some people don’t have any pain.

Around 7 p.m. — about two hours after we arrived — doctors explained our mother had an aortic dissection, a tear in the body's largest artery. She was rushed into emergency surgery, which ...