Myalept (metreleptin) has been approved in the US to treat the complications of leptin deficiency, in addition to diet, in patients with congenital generalized or acquired generalized lipodystrophy ...

Several open-label trials have demonstrated that administering metreleptin to correct overt hypoleptinemia significantly improves the metabolic abnormalities and insulin resistance in patients ...

VANCOUVER, British Columbia & CAMBRIDGE, Mass., April 04, 2017 (GLOBE NEWSWIRE) -- Novelion Therapeutics Inc. (NASDAQ:NVLN) (TSX:NVLN), a biopharmaceutical company dedicated to developing new ...

SAN DIEGO — Results from a new analysis of an ongoing, long-term research study of the investigational drug metreleptin, an analog of the human hormone leptin, demonstrated robust reductions in ...

DUBLIN, Ireland, and Boston MA, January 20, 2021, Amryt, a global, commercial-stage biopharmaceutical company dedicated to acquiring, developing and commercializing novel therapeutics to treat ...

Amylin Pharmaceuticals, Inc. (:AMLN) recently provided an update on its regulatory status for metreleptin.In an 8K filing with the US Securities and Exchange Commission (:SEC), Amylin said that ...

VANCOUVER, British Columbia and CAMBRIDGE, Mass., May 05, 2017 (GLOBE NEWSWIRE) -- Novelion Therapeutics Inc. (NASDAQ:NVLN) (TSX:NVLN), a biopharmaceutical company dedicated to developing new ...

HealthDay News — For patients with lipodystrophy (LD), resting-state connectivity is significantly increased in 3 brain areas with metreleptin treatment, with decreased hunger feelings and ...

- If approved, metreleptin would be the first medication available in the EU to treat generalized and partial lipodystrophies - More than 100 patients are currently treated with metreleptin via a ...

NIH study showed metreleptin treatment reduced HbA1c, triglycerides, and liver function tests in children and adolescents with lipodystrophy during a 12-month period.

* Patients treated with Metreleptin experienced clinically meaningful reductions from baseline in HBA1C, liver enzymes (AST, ALT), triglycerides * For patients assessed within one year of ...

Pediatrics > Obesity High-Dose Leptin Reversed Severe Genetic Obesity in Two Patients — Metreleptin doses several times higher than recommended brought weight down to near normal ...