Although metreleptin is administered subcutaneously, the lack of subcutaneous fat in these patients makes “each injection painful,” according to Svetlana Ten, MD, the study’s first author, a ...

Results In obese patients with diabetes, metreleptin administration for 16 weeks did not alter body weight or circulating inflammatory markers but reduced HbA 1c marginally (8.01 ± 0.93–7.96 ± ...

Worsening metabolic control and/or severe infection have been reported. Test for anti-metreleptin antibodies with neutralizing activity in patients with severe infections or loss of efficacy during ...

Pediatrics > Obesity High-Dose Leptin Reversed Severe Genetic Obesity in Two Patients — Metreleptin doses several times higher than recommended brought weight down to near normal by Kristen ...

Myalept®/Myalepta® (metreleptin) is approved in the US (under the trade name Myalept®) as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients ...

Amryt Receives Reimbursement Approval from the Dutch Ministry of Health for Myalepta® (metreleptin) DUBLIN, Ireland, and Boston MA, October 17, 2022, Amryt (Nasdaq: AMYT), a global, commercial-stage ...

Human recombinant leptin (metreleptin) is approved for the treatment of lipodystrophy. In these leptin-deficient patients, metreleptin lowers hepatic lipid content independent of food intake.

Human recombinant leptin (metreleptin) is approved for the treatment of lipodystrophy. In these leptin-deficient patients, metreleptin lowers hepatic lipid content independent of food intake.

Human recombinant leptin (metreleptin) is approved for the treatment of lipodystrophy. In these leptin-deficient patients, metreleptin lowers hepatic lipid content independent of food intake.

The year-on-year increase in metreleptin revenues was 49.9 per cent if the impact of a sporadic Latin America order from the second quarter of 2021 is excluded from the comparison.

Metreleptin revenues rocketed by 21.5% to US$36.3mln in the third quarter. Excluding Latin America, where ordering has been sporadic, sales of the drug were 51.6% higher.