Following the success of the first generation of monoclonal antibody ... many third-generation antibodies designed to trigger different mechanisms of action simultaneously (such as targeting ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

‘Mono’ means one and 'clone' means identical copy. Monoclonal antibodies are, therefore, identical copies of one type of antibody. Antibodies bind to specific antigens on pathogens. This means ...

Bispecific antibodies, which bind simultaneously to two different antigens, can attack tumors via novel mechanisms of action that cannot be evoked with combinations of conventional monoclonal ...

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The FDA granted orphan drug designation to HLX22 for gastric cancer, advancing global phase 3 trials to improve first-line ...

In an alopecia areata trial, a novel bifunctional therapy that blocks signaling of the interleukin-7 and TSLP pathways ...

Antibody-drug conjugates (ADCs ... and improve the safety profile of ADCs. The mechanism of action of bispecific ADCs ...