Detailed functional studies will be required to validate their implication in MDS pathogenesis. Mutations in genes encoding epigenetic regulators involved in DNA methylation and hydroxymethylation ...

Myelodysplastic syndromes (MDS) are clonal disorders of ... Different processes are involved in its pathogenesis, such as (epi)genetic alterations and immunological dysfunctions.

Myelodysplastic syndrome (MDS) can be difficult to diagnose. Many people who are diagnosed with MDS go to their doctor with some or all of the symptoms typical of MDS. Other people are diagnosed with ...

Study examines the effect of TP53 mutations on outcomes in MDS patients receiving haploidentical haematopoietic stem cell ...