TBI remained significantly associated with reduced adjusted risks of grade 3 to 4 aGVHD and moderate-severe cGVHD.

Myelodysplastic syndrome (MDS) involves abnormal production of blood cells in your bone marrow. MDS is not just one single disease. It is a group of diseases that affect how blood cells are made. In ...

has granted Orphan Drug designation to R289 for the treatment of myelodysplastic syndromes (MDS). R289 1, Rigel's potent and selective dual inhibitor of IRAK1 and IRAK4, is being studied in an ...

Study examines the effect of TP53 mutations on outcomes in MDS patients receiving haploidentical haematopoietic stem cell ...

An international research team has identified key genetic factors that confer protective effects against Alzheimer's disease (AD) through a comprehensive genetic analysis of East Asian populations, ...

Management of hematologic conditions including MDS and acute leukemias are particularly challenging among older adults due to variable coexisting comorbid conditions and functional status which can ...

Alopecia areata is a chronic autoimmune disorder causing non-scarring hair loss due to immune system attacks on hair follicles. Breakdown of immune privilege in hair follicles leads to ...

Syndromes are a group of signs and symptoms that often occur together but don't necessarily indicate a particular disease. Therefore, syndromes result from a variety of diseases or conditions and ...

Vitiligo is associated with increased cardiovascular disease risk, affecting organ function and metabolic syndrome ... and result from a complex pathogenesis that includes genetic factors ...

The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.