When you watch Patrick Dempsey movies or TV shows, you wouldn’t guess this boyishly handsome star has been in show biz for over 35 years. ... Will & Grace (2000-2001) ...

Actor Patrick Dempsey said during a recent interview he wants to work with Ellen Pompeo again. Dempsey starred as Derek "McDreamy" in "Grey's Anatomy." ...

Along with Patrick, she is co-founder of The Dempsey Center, a nonprofit cancer support center established in 2008 to honor their mother Amanda Dempsey who passed away in 2014 at age 79.