Patrick Dempsey’s role as McDreamy — a.k.a. Dr. Derek Shepherd — on Grey’s Anatomy might be his most iconic, but it’s not always the one he’s recognized for the most.. In a Dec. 4 ...

Patrick Dempsey says his eyes were opened when his mom was diagnosed with cancer. In an exclusive conversation with PEOPLE, the actor, 58, speaks candidly about his mom Amanda Dempsey's cancer ...

For Dempsey's part, that meant giving up his hobby of race car driving, as well as leaving "Gray's Anatomy" in April 2015 to focus more time on his family. "You can only do one thing at a time and ...

'Thanksgiving' director Eli Roth tells PEOPLE his holiday-themed slasher star Patrick Dempsey "just finally put McDreamy to bed" before he was named 2023's Sexiest Man Alive ...

You've never seen Patrick Dempsey and Sarah Michelle Gellar like this. The iconic TV stars have completely transformed for ...

You might know Patrick Dempsey from the 11 seasons he spent playing a neurosurgeon named Derek Shepherd, better known as McDreamy, on "Grey's Anatomy." (SOUNDBITE OF TV SHOW, ...

Patrick Dempsey is keeping it real. The actor, 58, opens up in this week's issue of PEOPLE about being named Sexiest Man Alive in 2023 , shortly before this year's pick will be revealed on Nov. 12.

Grey’s Anatomy fans were heartbroken after Patrick Dempsey‘s character Derek “McDreamy” Shepherd was killed off in season 11 of the show. However, a new book titled, How to Save a Life ...

Patrick, Jillian Dempsey share loving messages to each other: 'Life would not be the same without you' Patrick and Jillian Dempsey are celebrating a sweet milestone. 0:31.

Patrick Dempsey could be seen rallying participants, biking, leading the survivor walk and meeting people at the Dempsey Challenge this year. Posted September 21, 2024 Updated September 23, 2024 ...