The serum phenylalanine levels were determined by the fluorimetric method described by McCaman and Robins. 9 For these studies proteins were precipitated from 25 microliters of serum with an equal ...

Newer studies have similarly found that low levels of phenylalanine could be linked to major depressive disorder (11, 12). On the other hand, other older research shows no clear benefits.

D-phenylalanine: This is the synthetic form of L-phenylalanine. It has similar uses to L-phenylalanine, although scientists don't yet know if it has the same effects on the body as L-phenylalanine.

Sepiapterin significantly reduced blood phenylalanine levels in adult and pediatric patients with phenylketonuria (PKU), according to results from the APHENITY trial.

To the Editor: The paper by Sherman et al. in the April 16 issue of the Journal indicating vacuolization of bone-marrow cells in an infant on a diet low in phenylalanine is a most important and int ...

Pegvaliase, a phenylalanine (Phe)-metabolizing enzyme, is currently marketed under the brand name Palynziq ® to reduce blood Phe concentrations in adult patients with PKU who have uncontrolled ...

Only those who showed a reduction in phenylalanine levels of 15% or greater proceeded to the second part of the study. After a washout period, the responders were randomly assigned to receive the ...

Oral administration of this engineered probiotic can overcome the intestinal phenylalanine transfer bottleneck and more effectively reduce blood phenylalanine levels in mice with phenylketonuria.

Of those, 60 percent—or nine people—saw more than 20 percent reduction in their phenylalanine levels at either the one-week or two-week mark, which was measured via blood draws.

PTC Therapeutics, Inc. (NASDAQ: PTCT) announced today that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion on the ...