Interestingly, the respiratory epithelium within the olfactory cleft region is constituted by several cell populations, including secretory cells, ciliated cells, basal cells, submucosal Bowman ...

Intranasal instillation is used to deliver adenoviral vectors to the olfactory epithelium and respiratory tract. The success of this approach, however, has been tempered by inconsistent ...

SARS-CoV-2 primarily infects the OE and causes olfactory dysfunction in hACE2 mice. (A) Schematic diagram of experimental design. Briefly, groups of 6-8 weeks old hACE2 mice were infected with 5.4 ...

COVID-19-related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters. Science Translational Medicine , 2021; eabf8396 DOI ...

Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb. Cell , 2021; 184 (24): 5932 DOI: 10.1016/j.cell.2021.10.027 ...

In 1957 Suk Chul Chang 6 reported on the pathological changes in the bronchial epithelium of smokers as opposed to nonsmokers. In the former he found that the bronchial epithelium contained more ...

The lower respiratory tract consists of the trachea, bronchi and lungs. The air passages are lined with mucous membrane composed mainly of ciliated epithelium. Cilia constantly clean the tract and ...

Normal ciliated epithelium coloured in orange/red and NEK10 mutant epithelium in blue/green. Raghu Chivukula and Koch Institute Nanomaterials Core Facility The discovery of a gene’s key role in ...

Schematic representation of the MucilAir™ pseudostrati\u001Fed respiratory epithelium grown on the surface of a porous membrane with culture medium on the basal side and air on the apical ...

Neurons in the olfactory epithelium also offer an easy way for viruses to bypass traditional central nervous system barriers by providing a direct a pathway to the brain.