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The research found that specific microRNAs (miR-146a-5p and miR-221-3p) delivered by these vesicles could suppress LFH by inhibiting the TGF-β/SMAD4 signaling pathway, which is known to be ...

The clinical-stage biopharmaceutical company, specializing in treatments for disorders linked to dysfunctional signaling of the TGF-ß protein family, had previously suspended the 3.0 mg/kg and 4.5 ...