eLife2d
Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression
Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
Nature3d
Structure-based drug design articles from across Nature Portfolio
Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...
eLife3d
A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture
TEDC1 and TEDC2, functions in generating centriolar triplet microtubules, and that this is crucial for the proper formation of centriolar subdomains and the stability of centrioles throughout the cell ...
Investopedia4y
Organizational Chart: Types, Meaning, and How It Works
Investopedia / Yurle Villegas An organizational chart, or org chart, graphically represents an organization's structure by detailing the roles, responsibilities, and relationships between ...