What is lupus, and what does it do to your body? I just had a friend diagnosed with it after many months of tests. -- T.S.B.

A team studied the differences between monogenic and nonmonogenic lupus nephritis and the predictors of end-stage kidney disease. Monogenic lupus nephritis is distinct from non-monogenic disease with ...

A 35-year-old man presents with a chief complaint of purple discoloration of his toes and associated skin lesions that have ...

Dysregulation of the alternative complement pathway, hallmarked by isolated reduction of the serum C3 fraction, is now recognized as an additional feature of lupus nephritis. Persistent, isolated low ...

The U.S. Food and Drug Administration has approved GSK's autoinjector of Benlysta (belimumab) for subcutaneous injection in ...

Background Abnormalities of type I interferon signaling and production can initiate lupus development. Disturbances of nucleic acid-sensing molecules triggered autoreactivity in lupus mouse models.

But if you have lupus, your immune system doesn’t clear out the dead cells — and it attacks healthy cells instead. These attacks can lead to photosensitive lupus rashes and increase inflammation ...