The discovery of epidermal growth factor receptor (EGFR) mutations in non–small cell lung cancer (NSCLC) represented a groundbreaking advancement, shifting the treatment paradigm of these diseases ...

We determined that mural cells are a source for the C-X-C motif chemokine 12 (Cxcl12a and Cxcl12b), vascular endothelial growth factor C (Vegfc) and collagen and calcium-binding EGF domain-containing ...

Rizzuto I, Otter SJ, Bharathan R, Stewart A. Vascular endothelial growth factor (VEGF) inhibitors for the treatment of metastatic and recurrent cervical cancer (Protocol). Cochrane Database of ...

The migration of endothelial cells is crucial for angiogenesis. ... Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of ...

Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer Rongfang Wei 1,2 † Sixia Zhong 2 † Li ...

VEGFR2 binds smaller sub-types of VEGF-A, mature VEGF-C, mature VEGF-D and VEGF-E. Signaling from this receptor is the primary way in which endothelial cell migration, proliferation and survival ...

Leucocyte trans‐endothelial migration (KEGG, P = 9.71 × 10 −5) proteins were enriched in the FN adhesome, but not in the VEGF‐stimulated adhesome, suggesting our cells represent quiescent vasculature ...

We also tested hemangioma-derived stem cells for expression of vascular endothelial growth factor A ... The migration of endothelial cells was assayed as described previously. 10.

VEGF has been shown to regulate endothelial cell (EC) proliferation and migration. However, the nuclear mediators of the actions of VEGF in ECs have not been fully defined. We show that VEGF induces ...