The FDA plans to require new clinical trials for approval of annual COVID-19 boosters for healthy Americans under 65.

Federal health officials will no longer routinely approve annual COVID-19 shots for younger adults and children who are healthy

Moderna said on Wednesday it has withdrawn an application seeking approval for its flu and COVID combination vaccine candidate after discussions with the U.S. Food and Drug Administration.

Data shows around 300 deaths a week in mid-April as the FDA rolls out more-stringent vaccine approval rules.

The CEO of two live music venues has said the rising cost of living is causing his industry more problems than the coronavirus pandemic. David Gregg, who runs Albert's Shed live music venues in Shrewsbury and Telford, said: "At least during Covid there was some kind of light at the end of the tunnel and everyone was keen to get back to it."

The United States, traditionally the top donor to the UN health agency, was not part of the final stages of pandemic agreement process after the Trump administration announced a pullout from the WHO.