Childhood encephalopathy is an uncommon but significant paediatric presentation and is associated with significant mortality and long-term morbidity in survivors. By definition it is a somewhat ...

Objective To evaluate the efficacy and safety of early supplementation with insulin glargine (GI) during the acute management of paediatric diabetic ketoacidosis (DKA). Design Double-blinded ...

Design A prospective observational study over 1 year. Setting A District General Hospital, and Child and Adolescent Mental Health Department. Patients Children aged 8–18 years living in the catchment ...

Objective: The 6-minute walk test (6MWT) is an established measure of exercise capacity in adults and children with chronic cardiac or respiratory disease. Despite its widespread use, there are no ...

Kawasaki disease (KD) is an acute self-limiting inflammatory disorder, associated with vasculitis, affecting predominantly medium-sized arteries, particularly the coronary arteries. In developed ...

Background Recruitment of paediatric trainees is not matching its increasing demand. In 2019, only 69.8% of paediatric training program posts were filled, the lowest out of all UK programmes. Such ...

The concordance of nasal compared with nasopharyngeal swabs was assessed for the diagnosis of respiratory viral infections, and the degree of discomfort associated with each procedure was compared.

Aim Following the publication of the updated NICE guidelines1 recommending the use of standardised parenteral nutrition (PN) in preterm and term babies, alongside the known associated risks to patient ...

Joint hypermobility and genetic collagen disorders: are they related? If this same question had been posed a quarter of a century ago, the answer would have been very different from what is ...

Most children in hospital who are clinically deteriorating are monitored regularly, and their treatment is escalated effectively. However a small, but significant, number of deteriorating children ...

Background: Difficulty falling asleep (prolonged sleep latency) is a frequently reported problem in school-aged children. Aims: This study aimed to describe the distribution of sleep latency and ...

Aims: To conduct a prospective, community based study in an impoverished urban site in Kolkata (formerly Calcutta) in order to measure the burden of cholera, describe its epidemiology, and search for ...