Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

Background: Mouse models of colitis and cancer are indispensable for our understanding of the pathogenesis of these diseases. In the past, mice had to be sacrificed in order to analyse colitis ...

Objective The HBV HBx regulatory protein is required for transcription from the covalently closed circular DNA (cccDNA) minichromosome and affects the epigenetic control of both viral and host ...

Correspondence to Brian B Scott, Department of Medicine, Lincoln County Hospital, Lincoln LN2 5QY, UK; drbbscott{at}aol.com Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and postmenopausal ...

Correspondence to Professor Jingmei Jiang, Department of Epidemiology and Biostatistics, Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Basic Medical Sciences, ...

A simple technique for measuring gastrointestinal transit times using radioopaque pellets of barium-impregnated polythene has been developed and validated. A normal range has been established by ...

Correspondence to Dr Eileen Morgan, International Agency for Research on Cancer, 69372 Lyon CEDEX 08, France; morgane{at}iarc.who.int Objective Colorectal cancer (CRC) is the third most common cancer ...

Background Intestinal fibrosis resulting in stricture formation and obstruction in Crohn’s disease (CD) and increased wall stiffness leading to symptoms in ulcerative colitis (UC) is among the largest ...

Correspondence to: Dr M Prince, Centre for Liver Research, 4th Floor William Leech Building, Newcastle University Medical School, Framlington Place, Newcastle NE2 4HH, UK; Martin.prince{at}ncl.ac.uk ...

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Objective Given significant advances in treatment of viral hepatitis and the growing epidemic of obesity, the burden of the different types of liver diseases in the USA may be changing. Our aim was to ...

Correspondence to Dr G Nicholas Verne, Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112-2699, USA; gverne{at}tulane.edu Background More effective treatments are ...