Postmenopausal (PM) hormone therapy (HT) was extremely popular for years as a treatment for many conditions, including cardiovascular (CV) disease (CVD) prevention. The adverse results from the ...

Background Abnormal microcirculation has been suggested in hearts with pathological conditions, particularly in hypertrophic hearts, even in the presence of normal epicardial coronary arteries.

Patients with ischaemic heart disease and low ejection fraction (EF) are at increased risk of sudden death. MADIT (Multicenter Automated Defibrillator Implantation Trial) II has shown that implantable ...

Objectives We aimed to investigate whether digital home monitoring with centralised specialist support for remote management of heart failure (HF) is more effective in improving medical therapy and ...

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. It may cause symptoms such as palpitations, dyspnoea, fatigue, dizziness or chest discomfort. Mortality risk has been ...

In heart failure prognosis is related to the severity of impairment of functional capacity.1 The peak oxygen consumption (VO2) at cardiopulmonary exercise test (CPET) is considered the gold standard ...

Developed countries have enjoyed substantial falls in cardiovascular disease (CVD) mortality. However, low and middle income countries are drowning in a rising tide of CVD and other non-communicable ...

Background It is widely believed that cardiac rehabilitation following acute myocardial infarction (MI) reduces mortality by approximately 20%. This belief is based on systematic reviews and ...

The association of bicuspid aortic valve with aortic stenosis, aortic regurgitation, and infective endocarditis has been known for almost 150 years and with dissection of the aorta for 75 years.1These ...

In 1772, William Heberden described ‘a disorder of the breast marked with strong and peculiar symptoms… [with a] sense of strangling and anxiety’. Individuals affected are ‘seized while they are ...

Objective To examine the association between chocolate intake and the risk of future cardiovascular events. Methods We conducted a prospective study using data from the European Prospective ...

Methodology A literature review was carried out to analyse the effects of an increased intake of n3-PUFAs on vascular endothelial dysfunction. PubMed and SCOPUS were used to search for relevant ...