Among the many things columnist Candace Semien had to learn while living with lupus were the types and function of various ...

The cells can be obtained from the umbilical cord, bone marrow, adipose tissue, muscle, and the lungs. Researchers at the Medical University of South Carolina (MUSC) conducted a Phase 1 clinical trial ...

In patients with anti-dsDNA autoantibodies — a recognized biomarker for SLE — clinical response was achieved by a higher proportion of patients receiving Lupuzor (61.5%) than those receiving placebo ...

RC18 is a man-made protein designed to treat people with autoimmune conditions, such as SLE, by blocking the activity of two disease-causing proteins — the lymphocyte stimulator (BLyS) and the A ...

2. Eat foods rich in calcium Lupus patients may be under medication that can thin their bones as a side effect. Strengthen your bones (and avoid fractures), by eating foods that are high in calcium ...

“We are delighted with the news of the preliminary results of the Phase III confirmatory study of our proprietary novel fusion protein Telitacicept for the treatment of SLE in China,” Jianmin Fang, ...

Brepocitinib designed to block action of TYK2 and JAK1 enzymes Brepocitinib is a first-in-class oral medication designed to block the action of two enzymes — TYK2 and JAK1 — that are involved in ...

Type 1 interferon responses are implicated in a wide range of diseases, including SLE and CLE. Genetic mutations that activate these signaling pathways are also responsible for genetic forms of ...

In men that difference was lesser. Male patients with lupus lived a median of 61 years, and those in the public at large to age 73, a median 12-year difference. While septicemia and hypertension were ...

The study, “ VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease,” was published in the journal Science. Mitochondria are the small compartments in cells ...

The modified T-cells are then infused back into the patient’s body. When the T-cells’ CAR binds to CD19 on the patient’s B-cells, it triggers T-cells to attack and kill B-cells. The approach has been ...

The machine learning model was tested on 983 patients, who were not part of the initial datasets, to demonstrate that they could be classified into one of the eight endotypes. Each patient is given a ...