Cellular oxygen. Under normal conditions, the intracellular partial pressure of oxygen near mitochondria in a myocyte is very low, with reported values ranging from 1 to 10 mm Hg.15 It follows that ...

Objectives (1) Develop a programme theory of why, for whom and in what contexts integrated palliative care (PC) and heart failure (HF) services work/do not work; (2) use the programme theory to ...

Aims Heart failure (HF) has a lower public profile compared with other serious health conditions, notably cancer. This discourse analysis study investigates the extent to which HF is discussed in ...

Background Heart failure (HF) is associated with high levels of resource use and mortality, but prior UK studies have not compared outcomes by HF subtype (HF with reduced ejection fraction (HFrEF) and ...

Methods First, UK cardiovascular and non-cardiovascular mortality data were used to calculate the mean lifespan gain from an intervention (such as a statin) that reduces cardiovascular mortality by 30 ...

Background This study aimed to investigate the frequently overlooked symptoms of cold hypersensitivity and heavy legs related to varicose veins in a large sample of patients.Methods Data on 8782 ...

Objective Cardiovascular risk estimation is an essential step to reduce the onset of adverse cardiovascular events. For this purpose, the Systematic Coronary Risk Evaluation (SCORE) risk chart method ...

Introduction. Worldwide, an estimated 37 million people have a diagnosis of heart failure.1 2 The lifetime risk for developing heart failure is approximately 20%.3 The prevalence of heart failure is ...

The dissemination of scientific developments has conventionally been through two main platforms: medical journals and scientific conferences. In 1665, the Royal Society released the first medical ...

Background Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch ...

The publication of the Danish-German Cardiogenic Shock Trial (DANGER-SHOCK) earlier this year was therefore greeted with great enthusiasm.4 The trial randomised patients with STEMI-related CS to ...

Introduction Myxomas are the most frequent type of benign tumour of the heart, typically found in the left atrium. We present a case of myxoma with cardioembolic stroke coexisting with coronary artery ...