Neurofibrillary tangles mark Alzheimer’s disease and a plethora of primary tauopathies. How best to study them in the lab? Most mouse tauopathy models overexpress the human tau protein and are highly ...

Creating models for primary tauopathies sounds simple enough. Select a human tau gene variant that causes disease, stick it where the endogenous mouse gene sits in its genome, then wait a few months ...

Yanling Wang Rush University Contact Information Yanling Wang Chicago Professional Information Associate Professor Rush University ...

Now that doctors are prescribing anti-amyloid therapies for Alzheimer’s disease, scientists have begun to focus their energy on the other pathological hallmark of AD, neurofibrillary tangles. While ...

From April 24-25, the Tau Global Conference, a.k.a. Tau2025, drew 600 people to a hotel in Hyde Park, London, with 500 more following the science online. Attendance well surpassed Tau2020, the first, ...

Synonyms: High-copy SOD1-G93A, B6SJL.SOD1-G93A, Tg(hSOD1-G93A)1GUR mice, Gurney mice ...

Member Directory Profile Hadi Aly, B.S., C.S. Contact Information Hadi Aly, B.S., C.S. Burewala, Pakistan ...

Yoo Hyun Um, M.D., Ph.D.