Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.

The DNA damage response (DDR) plays an important role in maintaining genome stability (Jeggo et al, 2016). This is particularly apparent in cancer, where cells hijack DDR by upregulation of the key ...

Brain metastasis (BM) remains a significant challenge in breast cancer (BC) management. While conventional metastatic routes primarily involve hematogenous dissemination, emerging evidence suggests ...

The authors submitted a correction request while EMBO Press was conducting a data integrity investigation on the published article. Multiple data integrity issues affecting figures and datasets in the ...

A study by Senti et al (2025) now sheds light on the evolution of long terminal repeat (LTR) retrotransposons and endogenous retroviruses in D. melanogaster. The authors specifically focus on the ...

We identified a heterozygous missense mutation in IL36RN (IL36RN S113L) in a therapy-refractory Crohn’s disease patient. Functional assays and overexpression experiments demonstrated that this ...

Parthenolide is a natural compound that has shown highly promising anticancer activity. Even though its mode of action has been studied for decades, its antimitotic activity has been largely ...

I spent the winters of my youth traveling across Canada competing in cross-country ski races. Being the shortest kid in my high school, I was not designed at all to propel myself across snowy fields ...

Patient-derived xenograft (PDX) models are an essential resource in cancer research, enabling the discovery of novel molecular mechanisms and therapeutic targets, while providing a preclinical ...

Author Correction: Lactylation-driven FTO targets CDK2 to aggravate microvascular anomalies in diabetic retinopathy ...